Compared to other Las Vegas hotels, Main Street Station has an undeniable no-frills vibe. Main Street Station is guaranteed to offer a unique guest experience whether that ends up being a good or bad experience depends on what you’re looking for. Inquire about reserving a smoke-friendly room when you book. While Lexi does not offer any rooms that allow cigarette smoking, they do offer some marijuana-friendly rooms! The 4th floor of this 64-room hotel is a designated 420-friendly space with state-of-the-art air filtration systems in every room. Lexi Hotel is a small boutique hotel located off the Strip.